Halwel
NAD+ Nasal Spray — product photo

NAD+ Nasal Spray

from $125/moon the 12-month plan

NAD+ is a substance your cells already use to turn food into energy and support normal repair work. Halwel offers it as a compounded prescription nasal spray. Human studies have not proven that nasal NAD+ improves energy, focus, recovery, or longevity, so care begins with a clear goal and a planned check-in—not a promised result.

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$125/mo

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A licensed provider reviews every intake before treatment is prescribed.

FormulationNAD+ Nasal Spray 300mg/ml (15ml)

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How NAD+ Nasal Spray works

We would rather you understand the medicine than take our word for it.

It helps cells transfer energy

NAD+ stands for nicotinamide adenine dinucleotide. It is a helper molecule cells use when turning food into usable energy. Your cells need it to work normally. That fact alone does not show that an NAD+ nasal spray provides a health benefit.

Rajman et al., Cell Metabolism, 2018

It helps with normal cell repair and signaling

Cells also use NAD+ during DNA repair, stress responses, and communication inside the cell. These jobs explain why researchers are interested in NAD+. They do not prove that this nasal spray will improve a symptom or prevent disease.

Covarrubias et al., Nature Reviews Molecular Cell Biology, 2021

Levels can change with age and illness

The way the body makes and uses NAD+ can change with age, illness, and the type of tissue. A blood level does not necessarily show what is happening in every organ or predict how someone will feel.

Covarrubias et al., 2021

Thoughtful care in four clear steps

Hands holding a phone showing the Halwel intake questionnaire
1

Medical intake

Tell us about your health history, current medications, goals, and prior treatment. This is a medical screening, not a product order.

Patient at a kitchen table on a video visit with a clinician
2

Clinical review

A licensed clinician in your state independently decides whether treatment is appropriate. A prescription is not guaranteed.

Halwel package on a sunlit doorstep
3

Medication delivery

If prescribed, a licensed pharmacy prepares your medication and ships it in discreet packaging. Compounded medications are not FDA-approved.

Patient checking in with a clinician by phone from the front steps
4

Ongoing care

Use your portal for check-ins, dose questions, side effects, refills, and treatment changes. Your clinician can adjust or stop treatment based on your health and response.

What changes

The outcomes measured in trials, each with its source.

We understand what NAD+ does inside cells

Scientists understand many of the jobs NAD+ performs inside cells, including helping cells turn food into energy and communicate. This basic biology is the strongest part of the evidence.

Other substances can raise NAD+-related blood levels

Some human studies tested pills containing substances the body can use to make NAD+, such as nicotinamide riboside. Those pills raised some NAD+-related measurements in blood.

What to keep in mind: A pill containing a building block is not the same product or delivery method as NAD+ sprayed into the nose, so those results cannot tell us whether this nasal spray works.

Trammell et al., Nature Communications, 2016

We do not know what the nasal spray does for people

Published human studies have not shown that compounded nasal NAD+ improves energy, focus, mood, sleep, recovery, blood-sugar health, or lifespan. We do not know how much reaches the bloodstream or other tissues. We also do not know which dose works best or how safe long-term use is. A change in a blood test may not lead to a benefit someone can feel.

Start with something specific to measure

If a clinician considers treatment, you should agree on one specific symptom or ability to follow, a check-in date, and how much improvement would make treatment worth continuing. “Optimization” is too vague to measure.

NAD+ Nasal Spray questions

What patients ask most before starting. If yours isn't here, your clinician answers it during review.

Halwel offers a one-month plan for compounded NAD+ nasal spray if a clinician prescribes it. NAD+ is a helper molecule cells use to turn food into energy and support normal repair work. Its role inside cells is well understood, but nasal NAD+ has not been proven to improve general wellness or longevity.

Limited. We know far more about what NAD+ does inside cells and about pills containing NAD+ building blocks than we know about spraying NAD+ into the nose. Results from a different substance or delivery method cannot be assumed to apply to this product.

No. This is a compounded prescription. FDA has not reviewed it for safety, effectiveness, or quality, and it is not a generic version of an FDA-approved NAD+ nasal product.

It is a trial for a set period of time. Before starting, you and the clinician choose a specific goal, record where things stand, set a review date, and agree on reasons to continue or stop. It is not a promise that treatment will work.

Choose one or two concrete measures before starting—for example, the frequency or severity of a defined symptom or the ability to complete a specific activity. A vague sense of “optimization” is difficult to evaluate and can encourage indefinite treatment without evidence.

Follow the pharmacy label and your clinician’s instructions. They tell you how many sprays to use, how often, how to prepare and store the bottle, and when it expires. Do not copy directions from another product.

Nasal irritation, burning, dryness, congestion, unpleasant taste, headache, or nausea may occur. Because the exact product has limited trial data, report unexpected symptoms rather than assuming they are normal.

Stop and seek guidance for a concerning reaction. The care plan should also stop or change if there is no meaningful benefit by the agreed review date. It should change if safe use becomes difficult or a new health issue affects the decision.

The one-month plan includes one 15 mL bottle of compounded NAD+ nasal spray, with 300 mg of NAD+ in each milliliter, if prescribed. It also includes clinician review, follow-up support, and shipping. There is no separate membership fee. Your total charge and renewal timing are shown before you commit.

When you’re ready, begin with a short medical intake.

A licensed clinician will review your health and decide whether treatment is appropriate.

Check your eligibility →